This Is What Science Has to Say About Bromantane

Bromantane is anecdotally known for its benefits in a variety of applications, starting with cognitive function, and continuing with fatigue inhibition.

In any case, what interests people the most is whether or not Bromantane is safe.

Well, if you’re one of those people, the simpler answer is yes and no.

But for a more in-depth comprehension of this drug, keep reading to learn more.

What Is Bromantane?

Bromantane, also known by the trademark name of Ladasten is a drug designed in the 1980s in Russia. It is a derivative of adamantane, thus it is an actoprotector, which is a type of drug that improves physical activity.

It purportedly enhances energy levels, inhibits fatigue, reduces anxiety, improves learning, and promotes coordinate movement. All of the effects are claim to synergize together for an overall increase in peak mental and physical performance.

In Russian, bromantane is prescribed as a treatment for Neurasthenia. However, it can be bought OTC by any individual. It does not have an addictive profile, and poses no serious side-effects, according to the limited research that it has.

Even though the exact mechanism of action is unknown, some believe that it works by increasing neural activity in the hypothalamus nuclei, hippocampus, and reticular nuclei of the operculum.

It has a pro-cognitive effect on the dopamine system by raising the levels of tyrosine hydroxylase and the amino acid decarboxylase. This sensitized the dopamine formation from metabolized tyrosine.

Thus, through the increase in dopamine, alongside serotonin, bromantane improves wakefulness, alertness, and feelings of happiness.

For Neurasthenia

Neurasthenia is a medical condition that is recognized by headache, fatigue, insomnia, and mental weariness. In a month-long blind study of 700+ people who suffer from neurasthenia, 100 mg doses of bromantane have helped improve their sleep, and reduce symptoms. It has also improved quality of life with only 3% of patients experiencing side effects.

It has also affected brain activity levels in another study with the same condition. Patients with high levels of the alpha wave had experienced an increase in low-beta waves, and decreased high-beta waves. Whereas, those with low alpha waves have experienced the reverse.

This presumes that bromantane can increase your consciousness when awake, and wake up when you are drowsy. If these effects interest you, you should speak to your doctor about neurasthenia and potential treatments.

Enhanced Cognitive Function

In another study, bromantane has enhanced the patient’s vigilance, motor performance, and productivity. By increasing the levels of serotonin and dopamine, bromantane has contributed to wakefulness and alertness.

In a rat study, bromantane has improved the short-term memory, planning ability, attention, and motivation of the subjects. However, beyond the positive, at excessive dosages, it has inhibited the acetylcholine pathways.

Bromantane, when given to female rats, has helped the offspring with developing their reflexes faster than other rats, but in reality, the growth developmental variance was insignificant.

This leads to the insufficiency of information to support the characteristic of bromantane as a cognitive enhancer. More robust clinical trials are to be wished for, in order to confirm preliminary occurrences.

Enhanced Physical Activity

Bromantane is known to slightly increase noradrenaline and adrenaline in the blood. It has also contributed to the presence of both insides of the blood, instead of allowing it to exit the body via urine, thus increasing physical performance.

Rats that took bromantane have performed better at treadmill and swimming tests when given the bromantane. It also increases their blood pumped to the heart.

In some studies, bromantane shown to have a reducing effect on inflammation-induced depression. It decreased the inflammatory cytokines of IL-6, IL-17, IL-4, and TNF-Alpha.

In some reports, bromantane has stimulated the immune system during conditions of extreme stress by increasing the resistance to toxic agents. This is probably due to the increase of B-cell levels, which helps with fatigue recovery, low oxygen conditions, and environmental temperature.

The Side-Effects

Considering the non-existence of comprehensive testing, it’s hard to determine what the side effects are. In general, the only side-effects occur at high dosages of over 1000 mg per day.

It’s not habit-forming, thus it has no long-term addiction or withdrawal symptoms associated with it. Some adverse effects are counterintuitive to the intended action of the drug. For instance, brain fog, confusion, fatigue are all possible. In rare cases, insomnia, vomiting, and diarrhea are prevalent at high dosage.

It should not be taken before bed, as it would make falling asleep quite difficult. This page has more information on bromantane if you’re interested.

In any case, to understand the drug and how it will react with your body, it’s best to consult with a neurological specialist who can determine a course of action for your use of this substance, and if any contraindications are present with your current medication if any.

Bromantane Explained

Now that you know what bromantane is, what it can do, and what potential side effects it has, you can determine if it’s something you would like to try.

Bromantane is quite affordable, but that does not mitigate the potential risk associated with its consumption. If you’re going to try it, you might as well do as much research as possible. Visit the PubMed website or the National Library of Medicine online, and search the term “bromantane”, which will provide you with the entirety of available studies done on the drug.

If possible, speak to a neurological specialist who can determine if your body is capable of metabolizing the drug without side effects or contraindications.

If you’re interested in learning more about various health-related topics, go through our categorical pages and you will various articles on SARMs, PCT, Nootropics, and much more.


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